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Surgical margins in head and neck cancer: A contemporary review

Identifieur interne : 004950 ( Main/Exploration ); précédent : 004949; suivant : 004951

Surgical margins in head and neck cancer: A contemporary review

Auteurs : Michael L. Hinni [États-Unis] ; Alfio Ferlito [Italie] ; Margaret S. Brandwein-Gensler [États-Unis] ; Robert P. Takes [Pays-Bas] ; Carl E. Silver [États-Unis] ; William H. Westra [États-Unis] ; Raja R. Seethala [États-Unis] ; Juan P. Rodrigo [Espagne] ; June Corry [Australie] ; Carol R. Bradford [États-Unis] ; Jennifer L. Hunt [États-Unis] ; Primož Strojan [Slovénie] ; Kenneth O. Devaney [États-Unis] ; Douglas R. Gnepp [États-Unis] ; Dana M. Hartl [France] ; Luiz P. Kowalski [Brésil] ; Alessandra Rinaldo [Italie] ; Leon Barnes [États-Unis] ; David Eisele

Source :

RBID : ISTEX:362502F4D496F3CD233FEE858580056CEF767A3F

Descripteurs français

English descriptors

Abstract

Adequate resection margins are critical to the treatment decisions and prognosis of patients with head and neck squamous cell carcinoma (HNSCC). However, there are numerous controversies regarding reporting and interpretation of the status of resection margins. Fundamental issues relating to the basic definition of margin adequacy, uniform reporting standards for margins, optimal method of specimen dissection, and the role of intraoperative frozen section evaluation, all require further clarification and standardization. Future horizons for margin surveillance offer the possible use of novel methods such as “molecular margins” and contact microscopic endoscopy, However, the limitations of these approaches need to be understood. The goal of this review was to evaluate these issues to define a more rational, standardized approach for achieving resection margin adequacy for patients with HNSCC undergoing curative resection. © 2012 Wiley Periodicals, Inc. Head Neck, 2013

Url:
DOI: 10.1002/hed.23110


Affiliations:


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Le document en format XML

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<term>Growth pattern</term>
<term>Hazard ratio</term>
<term>Head neck</term>
<term>Head september</term>
<term>High risk</term>
<term>Histologic</term>
<term>Hnscc</term>
<term>Human papillomavirus</term>
<term>Inadequate margins</term>
<term>Intraoperative</term>
<term>Intraoperative evaluation</term>
<term>Intraoperative margin surveillance</term>
<term>Intraoperative microwave processing</term>
<term>Intraoperative resection margin surveillance</term>
<term>Laryngeal</term>
<term>Laryngeal cancer</term>
<term>Laryngectomy</term>
<term>Laser</term>
<term>Laser surgery</term>
<term>Local control</term>
<term>Local disease control</term>
<term>Local recurrence</term>
<term>Local tumor recurrence</term>
<term>Locoregional</term>
<term>Locoregional recurrence</term>
<term>Lymphovascular invasion</term>
<term>Margin</term>
<term>Margin adequacy</term>
<term>Margin assessment</term>
<term>Margin distance</term>
<term>Margin status</term>
<term>Margin surveillance</term>
<term>Maxillofac</term>
<term>Microscopic examination</term>
<term>Microsurgery</term>
<term>Molecular diagnosis</term>
<term>Molecular margins</term>
<term>Mucosal</term>
<term>Mucosal margins</term>
<term>Multivariate analysis</term>
<term>Narrow margins</term>
<term>Neck cancer</term>
<term>Neck cancer operations</term>
<term>Neck cancers</term>
<term>Neck surgery</term>
<term>Oncol</term>
<term>Optical techniques</term>
<term>Optimal method</term>
<term>Oral cancer</term>
<term>Oral cavity</term>
<term>Oral maxillofac surg</term>
<term>Oral oncol</term>
<term>Oropharyngeal</term>
<term>Otol rhinol laryngol</term>
<term>Otolaryngol</term>
<term>Otolaryngol head neck surg</term>
<term>Overall survival</term>
<term>Pathologist</term>
<term>Perineural invasion</term>
<term>Permanent pathology</term>
<term>Permanent sections</term>
<term>Positive margins</term>
<term>Postoperative</term>
<term>Postoperative radiotherapy</term>
<term>Primary tumor</term>
<term>Prognostic</term>
<term>Prognostic factors</term>
<term>Radiat oncol biol phys</term>
<term>Radiation oncology</term>
<term>Radiotherapy</term>
<term>Recurrence</term>
<term>Resected</term>
<term>Resected margins</term>
<term>Resected specimen</term>
<term>Resection</term>
<term>Resection margin adequacy</term>
<term>Resection margin standards</term>
<term>Resection margins</term>
<term>Resection specimen</term>
<term>Residual carcinoma</term>
<term>Section evaluation</term>
<term>Section margins</term>
<term>Section slide</term>
<term>September</term>
<term>Small size</term>
<term>Soft tissue margins</term>
<term>Squamous</term>
<term>Squamous cell carcinoma</term>
<term>Standardized approach</term>
<term>Supraglottic cancers</term>
<term>Surg</term>
<term>Surg oncol</term>
<term>Surg pathol</term>
<term>Surgeons need</term>
<term>Surgery</term>
<term>Surgical</term>
<term>Surgical defect</term>
<term>Surgical margin</term>
<term>Surgical margins</term>
<term>Surgical resection</term>
<term>Survival rates</term>
<term>Tissue shrinkage</term>
<term>Total laryngectomy</term>
<term>Transoral</term>
<term>Transoral laser microsurgery</term>
<term>Tumor cells</term>
<term>Tumor extension</term>
<term>Tumor factors</term>
<term>Tumor margins</term>
<term>Upper aerodigestive tract</term>
<term>Wpoi type</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Adjuvant</term>
<term>Chirurgie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Adequate resection margins are critical to the treatment decisions and prognosis of patients with head and neck squamous cell carcinoma (HNSCC). However, there are numerous controversies regarding reporting and interpretation of the status of resection margins. Fundamental issues relating to the basic definition of margin adequacy, uniform reporting standards for margins, optimal method of specimen dissection, and the role of intraoperative frozen section evaluation, all require further clarification and standardization. Future horizons for margin surveillance offer the possible use of novel methods such as “molecular margins” and contact microscopic endoscopy, However, the limitations of these approaches need to be understood. The goal of this review was to evaluate these issues to define a more rational, standardized approach for achieving resection margin adequacy for patients with HNSCC undergoing curative resection. © 2012 Wiley Periodicals, Inc. Head Neck, 2013</div>
</front>
</TEI>
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<li>Australie</li>
<li>Brésil</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Slovénie</li>
<li>États-Unis</li>
</country>
<region>
<li>Alabama</li>
<li>Arizona</li>
<li>Arkansas</li>
<li>Gueldre</li>
<li>Maryland</li>
<li>Michigan</li>
<li>Pennsylvanie</li>
<li>Rhode Island</li>
<li>État de New York</li>
<li>État de São Paulo</li>
<li>Île-de-France</li>
</region>
<settlement>
<li>Nimègue</li>
<li>Paris</li>
<li>São Paulo</li>
</settlement>
</list>
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<region name="Arizona">
<name sortKey="Hinni, Michael L" sort="Hinni, Michael L" uniqKey="Hinni M" first="Michael L." last="Hinni">Michael L. Hinni</name>
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<name sortKey="Barnes, Leon" sort="Barnes, Leon" uniqKey="Barnes L" first="Leon" last="Barnes">Leon Barnes</name>
<name sortKey="Bradford, Carol R" sort="Bradford, Carol R" uniqKey="Bradford C" first="Carol R." last="Bradford">Carol R. Bradford</name>
<name sortKey="Brandwein Ensler, Margaret S" sort="Brandwein Ensler, Margaret S" uniqKey="Brandwein Ensler M" first="Margaret S." last="Brandwein-Gensler">Margaret S. Brandwein-Gensler</name>
<name sortKey="Devaney, Kenneth O" sort="Devaney, Kenneth O" uniqKey="Devaney K" first="Kenneth O." last="Devaney">Kenneth O. Devaney</name>
<name sortKey="Gnepp, Douglas R" sort="Gnepp, Douglas R" uniqKey="Gnepp D" first="Douglas R." last="Gnepp">Douglas R. Gnepp</name>
<name sortKey="Hunt, Jennifer L" sort="Hunt, Jennifer L" uniqKey="Hunt J" first="Jennifer L." last="Hunt">Jennifer L. Hunt</name>
<name sortKey="Seethala, Raja R" sort="Seethala, Raja R" uniqKey="Seethala R" first="Raja R." last="Seethala">Raja R. Seethala</name>
<name sortKey="Silver, Carl E" sort="Silver, Carl E" uniqKey="Silver C" first="Carl E." last="Silver">Carl E. Silver</name>
<name sortKey="Westra, William H" sort="Westra, William H" uniqKey="Westra W" first="William H." last="Westra">William H. Westra</name>
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<country name="Italie">
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<name sortKey="Ferlito, Alfio" sort="Ferlito, Alfio" uniqKey="Ferlito A" first="Alfio" last="Ferlito">Alfio Ferlito</name>
</noRegion>
<name sortKey="Ferlito, Alfio" sort="Ferlito, Alfio" uniqKey="Ferlito A" first="Alfio" last="Ferlito">Alfio Ferlito</name>
<name sortKey="Ferlito, Alfio" sort="Ferlito, Alfio" uniqKey="Ferlito A" first="Alfio" last="Ferlito">Alfio Ferlito</name>
<name sortKey="Rinaldo, Alessandra" sort="Rinaldo, Alessandra" uniqKey="Rinaldo A" first="Alessandra" last="Rinaldo">Alessandra Rinaldo</name>
</country>
<country name="Pays-Bas">
<region name="Gueldre">
<name sortKey="Takes, Robert P" sort="Takes, Robert P" uniqKey="Takes R" first="Robert P." last="Takes">Robert P. Takes</name>
</region>
</country>
<country name="Espagne">
<noRegion>
<name sortKey="Rodrigo, Juan P" sort="Rodrigo, Juan P" uniqKey="Rodrigo J" first="Juan P." last="Rodrigo">Juan P. Rodrigo</name>
</noRegion>
<name sortKey="Rodrigo, Juan P" sort="Rodrigo, Juan P" uniqKey="Rodrigo J" first="Juan P." last="Rodrigo">Juan P. Rodrigo</name>
</country>
<country name="Australie">
<noRegion>
<name sortKey="Corry, June" sort="Corry, June" uniqKey="Corry J" first="June" last="Corry">June Corry</name>
</noRegion>
</country>
<country name="Slovénie">
<noRegion>
<name sortKey="Strojan, Primoz" sort="Strojan, Primoz" uniqKey="Strojan P" first="Primož" last="Strojan">Primož Strojan</name>
</noRegion>
</country>
<country name="France">
<noRegion>
<name sortKey="Hartl, Dana M" sort="Hartl, Dana M" uniqKey="Hartl D" first="Dana M." last="Hartl">Dana M. Hartl</name>
</noRegion>
<name sortKey="Hartl, Dana M" sort="Hartl, Dana M" uniqKey="Hartl D" first="Dana M." last="Hartl">Dana M. Hartl</name>
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<country name="Brésil">
<region name="État de São Paulo">
<name sortKey="Kowalski, Luiz P" sort="Kowalski, Luiz P" uniqKey="Kowalski L" first="Luiz P." last="Kowalski">Luiz P. Kowalski</name>
</region>
</country>
</tree>
</affiliations>
</record>

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